RNA Details
Disease Name
pulmonary fibrosis
Tissue
lung
RNA Symbol
mir-21
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
rattus norvegicus
Detection Methods
ELISA; qRT-PCR etc.
Target
NA
Pathway
STAT3-RELATED signaling pathway
PubMed ID
Title
Sulindac has strong antifibrotic effects by suppressing STAT3-related miR-21
Year
2015
Function
"By decreasing IFN-Y-induced STAT3/p-STAT3 expression to down-regulate miR-21, sulindac could significantly reverse EMT in A549 cells and prevent BLM-induced PF."